L1CAM Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90783-50, BS90783-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P32004(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC

All Applications: WB:1:1,000-1:5,000
IHC:1:50-1:200

Background: Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors, including neuroblastomas, rhabdomyosarcomas, Wilm's tumors, Ewing's sarcomas and some primitive myeloid malignancies. The NCAM-L1 adhesion molecule (CD171) plays an important role in axon guidance and cell migration in the nervous system. The presence of NCAM-L1 might contribute to tumor progression by promoting cell adhesion and migration and is known to be expressed by neurons, neuroblastomas and other malignant tumors.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: L1CAM polyclonal antibody detects endogenous levels of L1CAM protein.

Bioworld Molecular Weight: 85/250 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of L1CAM on different cells lysates using anti-L1CAM antibody at 1/500 dilution.
Positive control: Line 1: Hela Line 2: human brain, Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-L1CAM antibody. Counter stained with hematoxylin.

Alternative Name: N-CAM-L1, NCAM-L1, L1CAM, Antigen identified by monoclonal, R1, CAML1, CD171, CD171 antigen, HSAS, HSAS1, Hyd, L1, L1 cell adhesion molecule, L1-NCAM, L1cam, L1CAM, MASA, MIC5, N CAML1, N-CAM-L1, NCAM-L1, NCAML1, Nerve-growth factor-inducible large external glycoprotein, Neural cell adhesion molecule L1, NILE, OTTHUMP00000025992, S10, SPG1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified