LCN2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-60599-60, E-AB-60599-120, E-AB-60599-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: LCN2

Target Synonym: LCN2; 24p3; MSFI; NGAL; p25

Research Areas: Cancer, Cardiovascular, Metabolism, Immunology, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P80188

Background: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human LCN2 (NP_005555.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000 IF 1:50-1:200

Calculated MW: 22kDa

Observed MW: 22kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only